diff --git a/hw/xen/xen-operations.c b/hw/xen/xen-operations.c
index 3d213d28dfa6b7f617117520539dcdfc711b0e71..e00983ec4470e9d20d378bb8a83aa8033263468a 100644
--- a/hw/xen/xen-operations.c
+++ b/hw/xen/xen-operations.c
@@ -28,46 +28,13 @@
 #include <xenctrl.h>
 
 /*
- * We don't support Xen prior to 4.2.0.
+ * We don't support Xen prior to 4.7.1.
  */
 
-/* Xen 4.2 through 4.6 */
-#if CONFIG_XEN_CTRL_INTERFACE_VERSION < 40701
-
-typedef xc_evtchn xenevtchn_handle;
-typedef evtchn_port_or_error_t xenevtchn_port_or_error_t;
-
-#define xenevtchn_open(l, f) xc_evtchn_open(l, f);
-#define xenevtchn_close(h) xc_evtchn_close(h)
-#define xenevtchn_fd(h) xc_evtchn_fd(h)
-#define xenevtchn_pending(h) xc_evtchn_pending(h)
-#define xenevtchn_notify(h, p) xc_evtchn_notify(h, p)
-#define xenevtchn_bind_interdomain(h, d, p) xc_evtchn_bind_interdomain(h, d, p)
-#define xenevtchn_unmask(h, p) xc_evtchn_unmask(h, p)
-#define xenevtchn_unbind(h, p) xc_evtchn_unbind(h, p)
-
-typedef xc_gnttab xengnttab_handle;
-
-#define xengnttab_open(l, f) xc_gnttab_open(l, f)
-#define xengnttab_close(h) xc_gnttab_close(h)
-#define xengnttab_set_max_grants(h, n) xc_gnttab_set_max_grants(h, n)
-#define xengnttab_map_grant_ref(h, d, r, p) xc_gnttab_map_grant_ref(h, d, r, p)
-#define xengnttab_unmap(h, a, n) xc_gnttab_munmap(h, a, n)
-#define xengnttab_map_grant_refs(h, c, d, r, p) \
-    xc_gnttab_map_grant_refs(h, c, d, r, p)
-#define xengnttab_map_domain_grant_refs(h, c, d, r, p) \
-    xc_gnttab_map_domain_grant_refs(h, c, d, r, p)
-
-typedef xc_interface xenforeignmemory_handle;
-
-#else /* CONFIG_XEN_CTRL_INTERFACE_VERSION >= 40701 */
-
 #include <xenevtchn.h>
 #include <xengnttab.h>
 #include <xenforeignmemory.h>
 
-#endif
-
 /* Xen before 4.8 */
 
 static int libxengnttab_fallback_grant_copy(xengnttab_handle *xgt,
@@ -223,26 +190,6 @@ static struct gnttab_backend_ops libxengnttab_backend_ops = {
     .unmap = libxengnttab_backend_unmap,
 };
 
-#if CONFIG_XEN_CTRL_INTERFACE_VERSION < 40701
-
-static void *libxenforeignmem_backend_map(uint32_t dom, void *addr, int prot,
-                                          size_t pages, xfn_pfn_t *pfns,
-                                          int *errs)
-{
-    if (errs) {
-        return xc_map_foreign_bulk(xen_xc, dom, prot, pfns, errs, pages);
-    } else {
-        return xc_map_foreign_pages(xen_xc, dom, prot, pfns, pages);
-    }
-}
-
-static int libxenforeignmem_backend_unmap(void *addr, size_t pages)
-{
-    return munmap(addr, pages * XC_PAGE_SIZE);
-}
-
-#else /* CONFIG_XEN_CTRL_INTERFACE_VERSION >= 40701 */
-
 static void *libxenforeignmem_backend_map(uint32_t dom, void *addr, int prot,
                                           size_t pages, xen_pfn_t *pfns,
                                           int *errs)
@@ -256,8 +203,6 @@ static int libxenforeignmem_backend_unmap(void *addr, size_t pages)
     return xenforeignmemory_unmap(xen_fmem, addr, pages);
 }
 
-#endif
-
 struct foreignmem_backend_ops libxenforeignmem_backend_ops = {
     .map = libxenforeignmem_backend_map,
     .unmap = libxenforeignmem_backend_unmap,
diff --git a/include/hw/xen/xen_native.h b/include/hw/xen/xen_native.h
index 6bcc83baf9ebc6ae76e76ed40f710f18e1043ee8..f11eb423e347b2f797f26fc349a8706b4598e5b2 100644
--- a/include/hw/xen/xen_native.h
+++ b/include/hw/xen/xen_native.h
@@ -24,23 +24,11 @@
 extern xc_interface *xen_xc;
 
 /*
- * We don't support Xen prior to 4.2.0.
+ * We don't support Xen prior to 4.7.1.
  */
 
-/* Xen 4.2 through 4.6 */
-#if CONFIG_XEN_CTRL_INTERFACE_VERSION < 40701
-
-typedef xc_interface xenforeignmemory_handle;
-
-#define xenforeignmemory_open(l, f) xen_xc
-#define xenforeignmemory_close(h)
-
-#else /* CONFIG_XEN_CTRL_INTERFACE_VERSION >= 40701 */
-
 #include <xenforeignmemory.h>
 
-#endif
-
 extern xenforeignmemory_handle *xen_fmem;
 
 #if CONFIG_XEN_CTRL_INTERFACE_VERSION < 40900
@@ -148,8 +136,6 @@ static inline xendevicemodel_handle *xendevicemodel_open(
     return xen_xc;
 }
 
-#if CONFIG_XEN_CTRL_INTERFACE_VERSION >= 40500
-
 static inline int xendevicemodel_create_ioreq_server(
     xendevicemodel_handle *dmod, domid_t domid, int handle_bufioreq,
     ioservid_t *id)
@@ -211,8 +197,6 @@ static inline int xendevicemodel_set_ioreq_server_state(
     return xc_hvm_set_ioreq_server_state(dmod, domid, id, enabled);
 }
 
-#endif /* CONFIG_XEN_CTRL_INTERFACE_VERSION >= 40500 */
-
 static inline int xendevicemodel_set_pci_intx_level(
     xendevicemodel_handle *dmod, domid_t domid, uint16_t segment,
     uint8_t bus, uint8_t device, uint8_t intx, unsigned int level)
@@ -340,15 +324,6 @@ static inline int xen_get_vmport_regs_pfn(xc_interface *xc, domid_t dom,
 }
 #endif
 
-/* Xen before 4.6 */
-#if CONFIG_XEN_CTRL_INTERFACE_VERSION < 40600
-
-#ifndef HVM_IOREQSRV_BUFIOREQ_ATOMIC
-#define HVM_IOREQSRV_BUFIOREQ_ATOMIC 2
-#endif
-
-#endif
-
 static inline int xen_get_default_ioreq_server_info(domid_t dom,
                                                     xen_pfn_t *ioreq_pfn,
                                                     xen_pfn_t *bufioreq_pfn,
@@ -386,84 +361,6 @@ static inline int xen_get_default_ioreq_server_info(domid_t dom,
     return 0;
 }
 
-/* Xen before 4.5 */
-#if CONFIG_XEN_CTRL_INTERFACE_VERSION < 40500
-
-#ifndef HVM_PARAM_BUFIOREQ_EVTCHN
-#define HVM_PARAM_BUFIOREQ_EVTCHN 26
-#endif
-
-#define IOREQ_TYPE_PCI_CONFIG 2
-
-typedef uint16_t ioservid_t;
-
-static inline void xen_map_memory_section(domid_t dom,
-                                          ioservid_t ioservid,
-                                          MemoryRegionSection *section)
-{
-}
-
-static inline void xen_unmap_memory_section(domid_t dom,
-                                            ioservid_t ioservid,
-                                            MemoryRegionSection *section)
-{
-}
-
-static inline void xen_map_io_section(domid_t dom,
-                                      ioservid_t ioservid,
-                                      MemoryRegionSection *section)
-{
-}
-
-static inline void xen_unmap_io_section(domid_t dom,
-                                        ioservid_t ioservid,
-                                        MemoryRegionSection *section)
-{
-}
-
-static inline void xen_map_pcidev(domid_t dom,
-                                  ioservid_t ioservid,
-                                  PCIDevice *pci_dev)
-{
-}
-
-static inline void xen_unmap_pcidev(domid_t dom,
-                                    ioservid_t ioservid,
-                                    PCIDevice *pci_dev)
-{
-}
-
-static inline void xen_create_ioreq_server(domid_t dom,
-                                           ioservid_t *ioservid)
-{
-}
-
-static inline void xen_destroy_ioreq_server(domid_t dom,
-                                            ioservid_t ioservid)
-{
-}
-
-static inline int xen_get_ioreq_server_info(domid_t dom,
-                                            ioservid_t ioservid,
-                                            xen_pfn_t *ioreq_pfn,
-                                            xen_pfn_t *bufioreq_pfn,
-                                            evtchn_port_t *bufioreq_evtchn)
-{
-    return xen_get_default_ioreq_server_info(dom, ioreq_pfn,
-                                             bufioreq_pfn,
-                                             bufioreq_evtchn);
-}
-
-static inline int xen_set_ioreq_server_state(domid_t dom,
-                                             ioservid_t ioservid,
-                                             bool enable)
-{
-    return 0;
-}
-
-/* Xen 4.5 */
-#else
-
 static bool use_default_ioreq_server;
 
 static inline void xen_map_memory_section(domid_t dom,
@@ -624,6 +521,4 @@ static inline int xen_set_ioreq_server_state(domid_t dom,
                                                  enable);
 }
 
-#endif
-
 #endif /* QEMU_HW_XEN_NATIVE_H */
diff --git a/meson.build b/meson.build
index 553c8e0b9c56248b959d7f9367150b48adb14d62..0984237c48b69c2255cdf6584a222cb1752fc162 100644
--- a/meson.build
+++ b/meson.build
@@ -1683,16 +1683,13 @@ if get_option('xen').enabled() or (get_option('xen').auto() and have_system)
     endif
   endif
   if not xen.found()
-    xen_tests = [ '4.11.0', '4.10.0', '4.9.0', '4.8.0', '4.7.1', '4.6.0', '4.5.0', '4.2.0' ]
+    xen_tests = [ '4.11.0', '4.10.0', '4.9.0', '4.8.0', '4.7.1' ]
     xen_libs = {
       '4.11.0': [ 'xenstore', 'xenctrl', 'xendevicemodel', 'xenforeignmemory', 'xengnttab', 'xenevtchn', 'xentoolcore' ],
       '4.10.0': [ 'xenstore', 'xenctrl', 'xendevicemodel', 'xenforeignmemory', 'xengnttab', 'xenevtchn', 'xentoolcore' ],
       '4.9.0': [ 'xenstore', 'xenctrl', 'xendevicemodel', 'xenforeignmemory', 'xengnttab', 'xenevtchn' ],
       '4.8.0': [ 'xenstore', 'xenctrl', 'xenforeignmemory', 'xengnttab', 'xenevtchn' ],
       '4.7.1': [ 'xenstore', 'xenctrl', 'xenforeignmemory', 'xengnttab', 'xenevtchn' ],
-      '4.6.0': [ 'xenstore', 'xenctrl' ],
-      '4.5.0': [ 'xenstore', 'xenctrl' ],
-      '4.2.0': [ 'xenstore', 'xenctrl' ],
     }
     xen_deps = {}
     foreach ver: xen_tests
diff --git a/scripts/xen-detect.c b/scripts/xen-detect.c
index 85e8206490e7fc1c27e4f25cd15fdccc105528bf..db049e605cf9ab3ec07c568a1db7e6ac3559da49 100644
--- a/scripts/xen-detect.c
+++ b/scripts/xen-detect.c
@@ -138,66 +138,6 @@
     return 0;
   }
 
-#elif CONFIG_XEN_CTRL_INTERFACE_VERSION == 40600
-  #include <xenctrl.h>
-  #include <xenstore.h>
-  #include <stdint.h>
-  #include <xen/hvm/hvm_info_table.h>
-  #if !defined(HVM_MAX_VCPUS)
-  # error HVM_MAX_VCPUS not defined
-  #endif
-  int main(void) {
-    xc_interface *xc;
-    xs_daemon_open();
-    xc = xc_interface_open(0, 0, 0);
-    xc_hvm_set_mem_type(0, 0, HVMMEM_ram_ro, 0, 0);
-    xc_gnttab_open(NULL, 0);
-    xc_domain_add_to_physmap(0, 0, XENMAPSPACE_gmfn, 0, 0);
-    xc_hvm_inject_msi(xc, 0, 0xf0000000, 0x00000000);
-    xc_hvm_create_ioreq_server(xc, 0, HVM_IOREQSRV_BUFIOREQ_ATOMIC, NULL);
-    xc_reserved_device_memory_map(xc, 0, 0, 0, 0, NULL, 0);
-    return 0;
-  }
-
-#elif CONFIG_XEN_CTRL_INTERFACE_VERSION == 40500
-  #include <xenctrl.h>
-  #include <xenstore.h>
-  #include <stdint.h>
-  #include <xen/hvm/hvm_info_table.h>
-  #if !defined(HVM_MAX_VCPUS)
-  # error HVM_MAX_VCPUS not defined
-  #endif
-  int main(void) {
-    xc_interface *xc;
-    xs_daemon_open();
-    xc = xc_interface_open(0, 0, 0);
-    xc_hvm_set_mem_type(0, 0, HVMMEM_ram_ro, 0, 0);
-    xc_gnttab_open(NULL, 0);
-    xc_domain_add_to_physmap(0, 0, XENMAPSPACE_gmfn, 0, 0);
-    xc_hvm_inject_msi(xc, 0, 0xf0000000, 0x00000000);
-    xc_hvm_create_ioreq_server(xc, 0, 0, NULL);
-    return 0;
-  }
-
-#elif CONFIG_XEN_CTRL_INTERFACE_VERSION == 40200
-  #include <xenctrl.h>
-  #include <xenstore.h>
-  #include <stdint.h>
-  #include <xen/hvm/hvm_info_table.h>
-  #if !defined(HVM_MAX_VCPUS)
-  # error HVM_MAX_VCPUS not defined
-  #endif
-  int main(void) {
-    xc_interface *xc;
-    xs_daemon_open();
-    xc = xc_interface_open(0, 0, 0);
-    xc_hvm_set_mem_type(0, 0, HVMMEM_ram_ro, 0, 0);
-    xc_gnttab_open(NULL, 0);
-    xc_domain_add_to_physmap(0, 0, XENMAPSPACE_gmfn, 0, 0);
-    xc_hvm_inject_msi(xc, 0, 0xf0000000, 0x00000000);
-    return 0;
-  }
-
 #else
 #error invalid CONFIG_XEN_CTRL_INTERFACE_VERSION
 #endif